Health Ministry official said Remdesivir should be used with extreme caution (File)
New Delhi:
While the central government has indicated that drugs like remdesivir and tocilizumab are “investigational therapies” for the treatment of hospital patients with coronavirus, the Union’s Department of Health has alarmed all states, territories and ‘Union and medical college hospitals that their (drugs) used or used without discrimination the conditions for which they are not desirable can cause more harm than good.
In a videoconference with States on COVID case management, officials from the Ministry of Health stressed that in the absence of a cure, the clinical management protocol for COVID-19 from the Ministry of Health would be the most effective for standard treatment of light to moderate care. and severe cases of coronavirus.
“States have been informed that the available evidence for Remdesivir suggests that it may reduce the time for clinical improvement when used in moderate to severe cases. However, there has been no benefit in terms of mortality It should be used with extreme caution due to its potential for serious adverse effects, including liver and kidney damage, “said the official with the Ministry of Health.
Similarly, studies on tocilizumab have shown no benefit in reducing mortality. However, if used in patients with serious medical conditions, appropriate informed consent is required. Creeping use should be discouraged as the effect of the drug is directed against the “cykotin storm”, added the official.
“For mild cases, which account for almost 80% of the total cases, hydroxychloroquine (HCQ) has been recommended. Standard treatment strategies have shown positive results,” said the official.
According to the Ministry of Health, all “experimental therapies” should only be performed in appropriate health facilities where close monitoring of patients is possible in order to manage potential complications.
“The ICMR strongly recommended that clinical management continue to focus on oxygen therapy (including high-flow nasal oxygen), steroids (which are widely available and inexpensive), appropriate and timely administration of ‘High quality anti-coagulants and supportive care, including mental health counseling for patients and clinical management of pre-existing diseases and symptom alleviation,’ said an ICMR official.
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